Dimethyltryptamine (DMT)

Dose

Inhalation (most common route of administration)

Light: 10 – 20 mg

Common: 20 – 40 mg

Strong: 40 – 60 mg

Oral

Common: 30 – 60 mg

DMT is typically inactive orally. This changes when it is combined with an MAOI. An example of this combination is ayahuasca, which contains Banisteriopsis caapi (MAOIs) and Psychotria viridis (DMT).

An analysis of 16 ayahuasca preparations found the following concentrations per 100 mL:

• Beta-carboline (MAOI) average: 158 mg
  • Range: 20 – 401 mg
• DMT average: 29 mg
  • Range: 25 – 36 mg

Another analysis yielded a similar result, with a 100 mL dose providing an average of 24 mg of DMT.